t(3;11)(q25;p13) MBNL1/LMO2

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3407
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene Name	MBNL1
Location	3q25.1

Gene Name	LMO2
Location	11p13

Bibliography

Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2 by juxtaposition with MBNL1 and STAG2

Chen S, Nagel S, Schneider B, Kaufmann M, Meyer C, Zaborski M, Kees UR, Drexler HG, MacLeod RA

Leukemia 2011 Oct;25(10):1632-5

PMID 21647158

Translocations implicated (Data extracted from papers in the Atlas)

	t(3;11)(q25;p13) MBNL1/LMO2

External links

MBNL1 (3q25.1) LMO2 (11p13)

Mitelman database	t(3;11)(q25;p13) [Case List]    t(3;11)(q25;p13) [Transloc-MCList] MBNL1/LMO2 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:21:01 CET 2018

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