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t(3;11)(q25;p13) MBNL1/LMO2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3407
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameMBNL1
Location 3q25.1
Gene NameLMO2
Location 11p13

Bibliography

Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2 by juxtaposition with MBNL1 and STAG2
Chen S, Nagel S, Schneider B, Kaufmann M, Meyer C, Zaborski M, Kees UR, Drexler HG, MacLeod RA
Leukemia 2011 Oct;25(10):1632-5
PMID 21647158
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(3;11)(q25;p13) MBNL1/LMO2

External links

MBNL1 (3q25.1) LMO2 (11p13)

Mitelman databaset(3;11)(q25;p13) [Case List]    t(3;11)(q25;p13) [Transloc-MCList] MBNL1/LMO2 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:19:40 CEST 2018


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