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t(3;16)(q27;p12) IL21R/BCL6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3409
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Diffuse large B-cell lymphoma

Genes involved and Proteins

Gene NameIL21R
Location 16p12.1
Gene NameBCL6
Location 3q27.3

Bibliography

The gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphoma
Ueda C, Akasaka T, Kurata M, Maesako Y, Nishikori M, Ichinohasama R, Imada K, Uchiyama T, Ohno H
Oncogene 2002 Jan 17;21(3):368-76
PMID 11821949
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(3;16)(q27;p12) IL21R/BCL6

External links

IL21R (16p12.1) BCL6 (3q27.3)

Mitelman databaset(3;16)(q27;p12) [Case List]    t(3;16)(q27;p12) [Transloc-MCList] IL21R/BCL6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Mon Jul 9 10:13:44 CEST 2018


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