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t(3;21)(q26;q21) NRIP1/MECOM

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 1673
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene NameNRIP1
Gene NameMECOM
Location 3q26.2

Bibliography

Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases
Haferlach C, Bacher U, Grossmann V, Schindela S, Zenger M, Kohlmann A, Kern W, Haferlach T, Schnittger S
Genes Chromosomes Cancer 2012 Dec;51(12):1079-85
PMID 22887804
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(3;21)(q26;q21) NRIP1/MECOM

External links

NRIP1 () MECOM (3q26.2)

Mitelman databaset(3;21)(q26;q21) [Case List]    t(3;21)(q26;q21) [Transloc-MCList] NRIP1/MECOM [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:13:46 CEST 2018


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