| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3236 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
| Genes involved and Proteins |
| Gene Name | STIM2 |
| Location | 4p15.2 |
| Gene Name | IKZF1 |
| Location | 7p12.2 |
| Bibliography |
| Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia |
| Gu Z, Churchman M, Roberts K, Li Y, Liu Y, Harvey RC, McCastlain K, Reshmi SC, Payne-Turner D, Iacobucci I, Shao Y, Chen IM, Valentine M, Pei D, Mungall KL, Mungall AJ, Ma Y, Moore R, Marra M, Stonerock E, Gastier-Foster JM, Devidas M, Dai Y, Wood B, Borowitz M, Larsen EE, Maloney K, Mattano LA Jr, Angiolillo A, Salzer WL, Burke MJ, Gianni F, Spinelli O, Radich JP, Minden MD, Moorman AV, Patel B, Fielding AK, Rowe JM, Luger SM, Bhatia R, Aldoss I, Forman SJ, Kohlschmidt J, Mrózek K, Marcucci G, Bloomfield CD, Stock W, Kornblau S, Kantarjian HM, Konopleva M, Paietta E, Willman CL, Loh ML, Hunger SP, Mullighan CG |
| Nat Commun 2016 Nov 8;7:13331 |
| PMID 27824051 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(4;7)(p15;p12) STIM2/IKZF1 | |
| External links |
| Mitelman database | t(4;7)(p15;p12) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:34 CET 2020 |
For comments and suggestions or contributions, please contact us