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t(4;12)(q12;p13) ETV6/CHIC2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2700
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameCHIC2
Location 4q12

Bibliography

Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13)
Abe A, Mizuta S, Okamoto A, Yamamoto Y, Kameyama T, Mayeda A, Emi N
Int J Lab Hematol 2016 Apr;38(2):e15-8
PMID 26728794
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(4;12)(q12;p13) ETV6/CHIC2

External links

ETV6 (12p13.2) CHIC2 (4q12)

Mitelman databaset(4;12)(q12;p13) [Case List]    t(4;12)(q12;p13) [Transloc-MCList] ETV6/CHIC2 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Thu Aug 16 12:55:34 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.