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t(5;9)(q35;q34) SQSTM1/NUP214

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3227
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma|Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene NameSQSTM1
Location 5q35.3
Gene NameNUP214
Location 9q34.13

Bibliography

SQSTM1-NUP214: a new gene fusion in adult T-cell acute lymphoblastic leukemia
Gorello P, La Starza R, Di Giacomo D, Messina M, Puzzolo MC, Crescenzi B, Santoro A, Chiaretti S, Mecucci C
Haematologica 2010 Dec;95(12):2161-3
PMID 20851865
 
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG
Nature 2012 Jan 11;481(7380):157-63
PMID 22237106
 
Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia
Brown FC, Cifani P, Drill E, He J, Still E, Zhong S, Balasubramanian S, Pavlick D, Yilmazel B, Knapp KM, Alonzo TA, Meshinchi S, Stone RM, Kornblau SM, Marcucci G, Gamis AS, Byrd JC, Gonen M, Levine RL, Kentsis A
Br J Haematol 2017 Jan;176(1):86-91
PMID 27766616
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;9)(q35;q34) SQSTM1/NUP214

External links

SQSTM1 (5q35.3) NUP214 (9q34.13)

Mitelman databaset(5;9)(q35;q34) [Case List]    t(5;9)(q35;q34) [Transloc-MCList] SQSTM1/NUP214 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:06:02 CET 2018


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