Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(5;11)(q12;q23) CENPK::KMT2A

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Atlas_Id 2597
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute monoblastic leukemia without differentiation (FAB type M5a)

Genes involved and Proteins

Gene NameCENPK
Location 5q12.3
Gene NameKMT2A
Location 11q23.3


Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia
Taki T, Hayashi Y, Taniwaki M, Seto M, Ueda R, Hanada R, Suzukawa K, Yokota J, Morishita K
Oncogene 1996 Nov 21;13(10):2121-30
PMID 8950979

Translocations implicated (Data extracted from papers in the Atlas)

 t(5;11)(q12;q23) CENPK/KMT2A

External links

CENPK (5q12.3) KMT2A (11q23.3)

Mitelman databaset(5;11)(q12;q23)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Oct 8 16:38:29 CEST 2021

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