t(5;11)(q12;q23) CENPK/KMT2A

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute monoblastic leukemia without differentiation (FAB type M5a)

Genes Involved and Proteins

Gene name
CENPK
Location
5q12.3
Gene name
KMT2A
Location
11q23.3

Bibliography

Pubmed IDLast YearTitleAuthors
89509791996Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia.Taki T et al

Summary

Fusion gene

CENPK/KMT2A CENPK (5q12.3) KMT2A (11q23.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(5;11)(q12;q23) CENPK/KMT2A

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2597/t(5;11)(q12;q23)-cenpk-kmt2a