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t(5;11)(q23;q23) KMT2A/PRRC1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2894

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameKMT2A
Location 11q23.3
Gene NamePRRC1
Location 5q23.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

MLL partner genes in secondary acute lymphoblastic leukemia: report of a new partner PRRC1 and review of the literature
Douet-Guilbert N, Eveillard JR, Meyer C, Ugo V, Le Bris MJ, Basinko A, Morel F, Marschalek R, De Braekeleer M
Leuk Res 2014 Nov;38(11):1316-9
PMID 25205603
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;11)(q23;q23) KMT2A/PRRC1

External links

KMT2A (11q23.3) PRRC1 (5q23.2)

Mitelman databaset(5;11)(q23;q23) [Case List]    t(5;11)(q23;q23) [Transloc-MCList] KMT2A/PRRC1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:21:24 CET 2018


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