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t(5;11)(q31;p11) TCF7/SPI1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3249
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameTCF7
Location 5q31.1
Gene NameSPI1
Location 11p11.2

Bibliography

Recurrent SPI1 (PU
Seki M, Kimura S, Isobe T, Yoshida K, Ueno H, Nakajima-Takagi Y, Wang C, Lin L, Kon A, Suzuki H, Shiozawa Y, Kataoka K, Fujii Y, Shiraishi Y, Chiba K, Tanaka H, Shimamura T, Masuda K, Kawamoto H, Ohki K, Kato M, Arakawa Y, Koh K, Hanada R, Moritake H, Akiyama M, Kobayashi R, Deguchi T, Hashii Y, Imamura T, Sato A, Kiyokawa N, Oka A, Hayashi Y, Takagi M, Manabe A, Ohara A, Horibe K, Sanada M, Iwama A, Mano H, Miyano S, Ogawa S, Takita J
1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia Nat Genet
PMID 28671687
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;11)(q31;p11) TCF7/SPI1

External links

TCF7 (5q31.1) SPI1 (11p11.2)

Mitelman databaset(5;11)(q31;p11) [Case List]    t(5;11)(q31;p11) [Transloc-MCList] TCF7/SPI1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon May 14 13:42:56 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.