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t(5;12)(q32;q13) BIN2/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2554
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene NameBIN2
Location 12q13.13
Gene NamePDGFRB
Location 5q32

Bibliography

Fusion of PDGFRB to two distinct loci at 3p21 and a third at 12q13 in imatinib-responsive myeloproliferative neoplasms
Hidalgo-Curtis C, Apperley JF, Stark A, Jeng M, Gotlib J, Chase A, Cross NC, Grand FH
Br J Haematol 2010 Jan;148(2):268-73
PMID 20085582
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;12)(q32;q13) BIN2/PDGFRB

External links

BIN2 (12q13.13) PDGFRB (5q32)

Mitelman databaset(5;12)(q32;q13) [Case List]    t(5;12)(q32;q13) [Transloc-MCList] BIN2/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:14:04 CEST 2018


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