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t(5;14)(p15;q32) IGH/TERT

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2812
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma|Chronic lymphocytic leukemia

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameTERT
Location 5p15.33

Bibliography

Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies
Nagel I, Szczepanowski M, Martín-Subero JI, Harder L, Akasaka T, Ammerpohl O, Callet-Bauchu E, Gascoyne RD, Gesk S, Horsman D, Klapper W, Majid A, Martinez-Climent JA, Stilgenbauer S, Tönnies H, Dyer MJ, Siebert R
Blood 2010 Aug 26;116(8):1317-20
PMID 20460502
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;14)(p15;q32) IGH/TERT

External links

IGH (14q32.33) TERT (5p15.33)

Mitelman databaset(5;14)(p15;q32) [Case List]    t(5;14)(p15;q32) [Transloc-MCList] IGH/TERT [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:06:10 CET 2018


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jlhuret@AtlasGeneticsOncology.org.