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t(5;14)(q32;q22) NIN/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3426
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene NameNIN
Location 14q22.1
Gene NamePDGFRB
Location 5q32

Bibliography

NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder
Vizmanos JL, Novo FJ, Román JP, Baxter EJ, Lahortiga I, Larráyoz MJ, Odero MD, Giraldo P, Calasanz MJ, Cross NC
Cancer Res 2004 Apr 15;64(8):2673-6
PMID 15087377
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;14)(q32;q22) NIN/PDGFRB

External links

NIN (14q22.1) PDGFRB (5q32)

Mitelman databaset(5;14)(q32;q22) [Case List]    t(5;14)(q32;q22) [Transloc-MCList] NIN/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:20:09 CEST 2018


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