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t(5;14)(q35;q11) TRD/TLX3

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3298
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameTRD
Location 14q11.2
Gene NameTLX3
Location 5q35.1

Bibliography

Disruption of the RanBP17/Hox11L2 region by recombination with the TCRdelta locus in acute lymphoblastic leukemias with t(5;14)(q34;q11)
Hansen-Hagge TE, Schäfer M, Kiyoi H, Morris SW, Whitlock JA, Koch P, Bohlmann I, Mahotka C, Bartram CR, Janssen JW
Leukemia 2002 Nov;16(11):2205-12
PMID 12399963
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;14)(q35;q11) TRD/TLX3

External links

TRD (14q11.2) TLX3 (5q35.1)

Mitelman databaset(5;14)(q35;q11) [Case List]    t(5;14)(q35;q11) [Transloc-MCList] TRD/TLX3 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:20:10 CEST 2018


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