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t(5;17)(q32;p11) MPRIP/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2976
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Myelodysplastic/myeloproliferative disease, NOS

Genes involved and Proteins

Gene NameMPRIP
Location 17p11.2
Gene NamePDGFRB
Location 5q32

Bibliography

Fusion of PDGFRB to MPRIP, CPSF6, and GOLGB1 in three patients with eosinophilia-associated myeloproliferative neoplasms
Naumann N, Schwaab J, Metzgeroth G, Jawhar M, Haferlach C, Göhring G, Schlegelberger B, Dietz CT, Schnittger S, Lotfi S, Gärtner M, Dang TA, Hofmann WK, Cross NC, Reiter A, Fabarius A
Genes Chromosomes Cancer 2015 Dec;54(12):762-70
PMID 26355392
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;17)(q32;p11) MPRIP/PDGFRB

External links

MPRIP (17p11.2) PDGFRB (5q32)

Mitelman databaset(5;17)(q32;p11) [Case List]    t(5;17)(q32;p11) [Transloc-MCList] MPRIP/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:20:13 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.