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t(5;20)(q32;p11) DTD1/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2666

Clinics and Pathology

Disease Chronic eosinophilic leukemia/hypereosinophilic syndrome

Genes involved and Proteins

Gene NameDTD1
Location 20p11.23
Gene NamePDGFRB
Location 5q32

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Identification and functional characterization of imatinib-sensitive DTD1-PDGFRB and CCDC88C-PDGFRB fusion genes in eosinophilia-associated myeloid/lymphoid neoplasms
Gosenca D, Kellert B, Metzgeroth G, Haferlach C, Fabarius A, Schwaab J, Kneba M, Scheid C, Töpelt K, Erben P, Haferlach T, Cross NC, Hofmann WK, Seifarth W, Reiter A
Genes Chromosomes Cancer 2014 May;53(5):411-21
PMID 24772479
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;20)(q32;p11) DTD1/PDGFRB

External links

DTD1 (20p11.23) PDGFRB (5q32)

Mitelman databaset(5;20)(q32;p11) [Case List]    t(5;20)(q32;p11) [Transloc-MCList] DTD1/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:21:32 CET 2018


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jlhuret@AtlasGeneticsOncology.org.