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t(5;20)(q32;p11) PDGFRB/DTD1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3085

Clinics and Pathology

Disease Chronic eosinophilic leukemia/hypereosinophilic syndrome

Genes involved and Proteins

Gene NamePDGFRB
Location 5q32
Gene NameDTD1
Location 20p11.23

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Targeted next-generation sequencing detects point mutations, insertions, deletions and balanced chromosomal rearrangements as well as identifies novel leukemia-specific fusion genes in a single procedure
Grossmann V, Kohlmann A, Klein HU, Schindela S, Schnittger S, Dicker F, Dugas M, Kern W, Haferlach T, Haferlach C
Leukemia 2011 Apr;25(4):671-80
PMID 21252984
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;20)(q32;p11) PDGFRB/DTD1

External links

PDGFRB (5q32) DTD1 (20p11.23)

Mitelman databaset(5;20)(q32;p11) [Case List]    t(5;20)(q32;p11) [Transloc-MCList] PDGFRB/DTD1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:21:32 CET 2018


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jlhuret@AtlasGeneticsOncology.org.