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t(5;21)(q21;q22) CHD1/RUNX1

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 2603

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

Genes involved and Proteins

Gene NameCHD1
Location 5q15-q21.1
Gene NameRUNX1
Location 21q22.12

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute


Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22)
Yao H, Pan J, Wu C, Shen H, Xie J, Wang Q, Wen L, Wang Q, Ma L, Wu L, Ping N, Zhao Y, Sun A, Chen S
Mol Cancer 2015 Apr 11;14:81
PMID 25879624

Translocations implicated (Data extracted from papers in the Atlas)

 t(5;21)(q21;q22) CHD1/RUNX1

External links

CHD1 (5q15-q21.1) RUNX1 (21q22.12)

Mitelman databaset(5;21)(q21;q22) [Case List]    t(5;21)(q21;q22) [Transloc-MCList] CHD1/RUNX1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:23:50 CET 2018

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