Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(5;21)(q21;q22) CHD1/RUNX1

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Atlas_Id 2603
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

Genes involved and Proteins

Gene NameCHD1
Location 5q15
Gene NameRUNX1
Location 21q22.12


Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22)
Yao H, Pan J, Wu C, Shen H, Xie J, Wang Q, Wen L, Wang Q, Ma L, Wu L, Ping N, Zhao Y, Sun A, Chen S
Mol Cancer 2015 Apr 11;14:81
PMID 25879624

Translocations implicated (Data extracted from papers in the Atlas)

 t(5;21)(q21;q22) CHD1/RUNX1

External links

CHD1 (5q15) RUNX1 (21q22.12)

Mitelman databaset(5;21)(q21;q22)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:27:48 CET 2020

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