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t(6;8)(p21;q24) MYC/SUPT3H

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2987

Clinics and Pathology

Disease Acute myeloid leukemia, special type

Genes involved and Proteins

Gene NameMYC
Location 14q23.3
Gene NameSUPT3H
Location 6p21.1

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Identification of SUPT3H as a novel 8q24/MYC partner in blastic plasmacytoid dendritic cell neoplasm with t(6;8)(p21;q24) translocation
Nakamura Y, Kayano H, Kakegawa E, Miyazaki H, Nagai T, Uchida Y, Ito Y, Wakimoto N, Mori S, Bessho M
Blood Cancer J 2015 Apr 10;5:e301
PMID 25860292
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;8)(p21;q24) MYC/SUPT3H

External links

MYC (14q23.3) SUPT3H (6p21.1)

Mitelman databaset(6;8)(p21;q24) [Case List]    t(6;8)(p21;q24) [Transloc-MCList] MYC/SUPT3H [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:21:36 CET 2018


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jlhuret@AtlasGeneticsOncology.org.