Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(6;10)(q27;q11) FGFR1OP::RET

(Note : for Links provided by Atlas : click)


Atlas_Id 2727
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic myelomonocytic leukemia|Idiopathic myelofibrosis

Genes involved and Proteins

Gene NameFGFR1OP
Location 6q27
Gene NameRET
Location 10q11.21


RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation
Ballerini P, Struski S, Cresson C, Prade N, Toujani S, Deswarte C, Dobbelstein S, Petit A, Lapillonne H, Gautier EF, Demur C, Lippert E, Pages P, Mansat-De Mas V, Donadieu J, Huguet F, Dastugue N, Broccardo C, Perot C, Delabesse E
Leukemia 2012 Nov;26(11):2384-9
PMID 22513837
Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies
Bossi D, Carlomagno F, Pallavicini I, Pruneri G, Trubia M, Raviele PR, Marinelli A, Anaganti S, Cox MC, Viale G, Santoro M, Di Fiore PP, Minucci S
Mol Oncol 2014 Mar;8(2):221-31
PMID 24315414

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;10)(q27;q11) FGFR1OP/RET

External links

FGFR1OP (6q27) RET (10q11.21)

Mitelman databaset(6;10)(q27;q11)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Oct 8 16:38:41 CEST 2021

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