t(6;11)(q15;q23) KMT2A/CASP8AP2

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute myeloblastic leukemia with maturation (FAB type M2)|Acute myeloid leukemia, NOS

Genes Involved and Proteins

Gene name
KMT2A
Location
11q23.3
Gene name
CASP8AP2
Location
6q15

Bibliography

Pubmed IDLast YearTitleAuthors
198372772009CASP8AP2 is a novel partner gene of MLL rearrangement with t(6;11)(q15;q23) in acute myeloid leukemia.Park TS et al
236289582013The MLL recombinome of acute leukemias in 2013.Meyer C et al

Summary

Fusion gene

KMT2A/CASP8AP2 KMT2A (11q23.3) CASP8AP2 (6q15)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(6;11)(q15;q23) KMT2A/CASP8AP2

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2870/t(6;11)(q15;q23)-kmt2a-casp8ap2