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t(6;12)(q22;p13) ETV6/RNF217

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2713
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameRNF217
Location 6q22.31

Bibliography

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line
Suto Y, Sato Y, Smith SD, Rowley JD, Bohlander SK
Genes Chromosomes Cancer 1997 Apr;18(4):254-68
PMID 9087565
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;12)(q22;p13) ETV6/RNF217

External links

ETV6 (12p13.2) RNF217 (6q22.31)

Mitelman databaset(6;12)(q22;p13) [Case List]    t(6;12)(q22;p13) [Transloc-MCList] ETV6/RNF217 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:20:26 CEST 2018


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