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t(6;12)(q22;q24) NCOR2/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 1765

Clinics and Pathology

Disease -

Genes involved and Proteins

Gene NameNCOR2
Location 12q24.31
Gene NameROS1
Location 3q11.1

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma
Crescenzo R, Abate F, Lasorsa E, Tabbo' F, Gaudiano M, Chiesa N, Di Giacomo F, Spaccarotella E, Barbarossa L, Ercole E, Todaro M, Boi M, Acquaviva A, Ficarra E, Novero D, Rinaldi A, Tousseyn T, Rosenwald A, Kenner L, Cerroni L, Tzankov A, Ponzoni M, Paulli M, Weisenburger D, Chan WC, Iqbal J, Piris MA, Zamo' A, Ciardullo C, Rossi D, Gaidano G, Pileri S, Tiacci E, Falini B, Shultz LD, Mevellec L, Vialard JE, Piva R, Bertoni F, Rabadan R, Inghirami G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies”
Cancer Cell 2015 Apr 13;27(4):516-32
PMID 25873174
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;12)(q22;q24) NCOR2/ROS1

External links

NCOR2 (12q24.31) ROS1 (3q11.1)

Mitelman databaset(6;12)(q22;q24) [Case List]    t(6;12)(q22;q24) [Transloc-MCList] NCOR2/ROS1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:21:40 CET 2018


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jlhuret@AtlasGeneticsOncology.org.