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t(6;22)(p21;q11) IGL/CCND3

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2826

Clinics and Pathology

Disease Multiple myeloma

Genes involved and Proteins

Gene NameIGL
Location 19q13.41
Gene NameCCND3
Location 6p21.1

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma
Shaughnessy J Jr, Gabrea A, Qi Y, Brents L, Zhan F, Tian E, Sawyer J, Barlogie B, Bergsagel PL, Kuehl M
Blood 2001 Jul 1;98(1):217-23
PMID 11418483
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;22)(p21;q11) IGL/CCND3

External links

IGL (19q13.41) CCND3 (6p21.1)

Mitelman databaset(6;22)(p21;q11) [Case List]    t(6;22)(p21;q11) [Transloc-MCList] IGL/CCND3 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Fri Feb 23 20:23:59 CET 2018


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