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t(6;22)(p21;q11) IGL/CCND3

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2826
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Multiple myeloma

Genes involved and Proteins

Gene NameIGL
Location 19q13.41
Gene NameCCND3
Location 6p21.1

Bibliography

Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma
Shaughnessy J Jr, Gabrea A, Qi Y, Brents L, Zhan F, Tian E, Sawyer J, Barlogie B, Bergsagel PL, Kuehl M
Blood 2001 Jul 1;98(1):217-23
PMID 11418483
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(6;22)(p21;q11) IGL/CCND3

External links

IGL (19q13.41) CCND3 (6p21.1)

Mitelman databaset(6;22)(p21;q11) [Case List]    t(6;22)(p21;q11) [Transloc-MCList] IGL/CCND3 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:14:23 CEST 2018


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