t(7;7)(p12;p22) GRB10/SDK1

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute megakaryoblastic leukemia (FAB type M7)

Genes Involved and Proteins

Gene name
GRB10
Location
7p12.1
Gene name
SDK1
Location
7p22.2

Bibliography

Pubmed IDLast YearTitleAuthors
231535402012An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.Gruber TA et al

Summary

Fusion gene

GRB10/SDK1 GRB10 (7p12.1) SDK1 (7p22.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(7;7)(p12;p22) GRB10/SDK1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2755/t(7;7)(p12;p22)-grb10-sdk1