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t(7;7)(q21;q21) FAM133B/CDK6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2721

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameFAM133B
Location 7q21.2
Gene NameCDK6
Location 7q21.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types
Giacomini CP, Sun S, Varma S, Shain AH, Giacomini MM, Balagtas J, Sweeney RT, Lai E, Del Vecchio CA, Forster AD, Clarke N, Montgomery KD, Zhu S, Wong AJ, van de Rijn M, West RB, Pollack JR
PLoS Genet 2013 Apr;9(4):e1003464
PMID 23637631
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;7)(q21;q21) FAM133B/CDK6

External links

FAM133B (7q21.2) CDK6 (7q21.2)

Mitelman databaset(7;7)(q21;q21) [Case List]    t(7;7)(q21;q21) [Transloc-MCList] FAM133B/CDK6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:24:03 CET 2018


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jlhuret@AtlasGeneticsOncology.org.