t(7;8)(q22;p11) CUX1/FGFR1

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
CUX1
Location
7q22.1
Gene name
FGFR1
Location
8p11.23

Highly cited references

Pubmed IDYearTitleCitations
272451472016FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).130
213303212011The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11).20

Bibliography

Pubmed IDLast YearTitleAuthors
213303212011The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11).Wasag B et al

Summary

Fusion gene

CUX1/FGFR1 CUX1 (7q22.1) FGFR1 (8p11.23)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

t(7;8)(q22;p11) CUX1/FGFR1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2641/t(7;8)(q22;p11)-cux1-fgfr1