t(7;9)(p22;q34) NUP214/RAC1

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	1114
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute myeloblastic leukemia with maturation (FAB type M2)

Genes involved and Proteins

Gene Name	NUP214
Location	9q34.13

Gene Name	RAC1
Location	7p22.1

Bibliography

NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214

Abe A, Yamamoto Y, Iba S, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Kanie T, Tsuzuki M, Akatsuka Y, Mizuta S, Okamoto M, Kameyama T, Mayeda A, Emi N

Cytogenet Genome Res 2015;146(4):279-84

PMID 26517539

Translocations implicated (Data extracted from papers in the Atlas)

	t(7;9)(p22;q34) NUP214/RAC1

External links

NUP214 (9q34.13) RAC1 (7p22.1)

Mitelman database	t(7;9)(p22;q34) [Case List]    t(7;9)(p22;q34) [Transloc-MCList] NUP214/RAC1 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Nov 6 14:06:41 CET 2018

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