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t(7;9)(q11;p13) PAX5/AUTS2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3435
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NamePAX5
Location 9p13.2
Gene NameAUTS2
Location 7q11.22

Bibliography

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray
Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP
Proc Natl Acad Sci U S A 2008 Aug 19;105(33):11921-6
PMID 18697940
 
PAX5-AUTS2 fusion resulting from t(7;9)(q11
Coyaud E, Struski S, Dastugue N, Brousset P, Broccardo C, Bradtke J
2;p13 2) can now be classified as recurrent in B cell acute lymphoblastic leukemia
PMID 20723977
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;9)(q11;p13) PAX5/AUTS2

External links

PAX5 (9p13.2) AUTS2 (7q11.22)

Mitelman databaset(7;9)(q11;p13) [Case List]    t(7;9)(q11;p13) [Transloc-MCList] PAX5/AUTS2 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:20:38 CEST 2018


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For comments and suggestions or contributions, please contact us

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