t(7;11)(p15;p15) NUP98/HOXA11

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3037
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute myeloblastic leukemia with maturation (FAB type M2)|Chronic myeloid leukemia, t(9;22)|Juvenile myelomonocytic leukemia

Genes involved and Proteins

Gene Name	NUP98
Location	11p15.4

Gene Name	HOXA11
Location	7p15.2

Bibliography

Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15)

Fujino T, Suzuki A, Ito Y, Ohyashiki K, Hatano Y, Miura I, Nakamura T

Blood 2002 Feb 15;99(4):1428-33

PMID 11830496

t(7;11)(p15;p15) Chronic myeloid leukaemia developed into blastic transformation showing a novel NUP98/HOXA11 fusion

Suzuki A, Ito Y, Sashida G, Honda S, Katagiri T, Fujino T, Nakamura T, Ohyashiki K

Br J Haematol 2002 Jan;116(1):170-2

PMID 11841413

Juvenile myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98-HOXA11 fusion

Mizoguchi Y, Fujita N, Taki T, Hayashi Y, Hamamoto K

Am J Hematol 2009 May;84(5):295-7

PMID 19338047

Translocations implicated (Data extracted from papers in the Atlas)

	t(7;11)(p15;p15) NUP98/HOXA11

External links

NUP98 (11p15.4) HOXA11 (7p15.2)

Mitelman database	t(7;11)(p15;p15) [Case List]    t(7;11)(p15;p15) [Transloc-MCList] NUP98/HOXA11 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 8 15:29:45 CEST 2019

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