t(7;11)(p15;p15) NUP98/HOXA11

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute myeloblastic leukemia with maturation (FAB type M2)|Chronic myeloid leukemia, t(9;22)|Juvenile myelomonocytic leukemia

Genes Involved and Proteins

Gene name
NUP98
Location
11p15.4
Gene name
HOXA11
Location
7p15.2

Highly cited references

Pubmed IDYearTitleCitations
193380472009Juvenile myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98-HOXA11 fusion.10
118414132002t(7;11)(p15;p15) Chronic myeloid leukaemia developed into blastic transformation showing a novel NUP98/HOXA11 fusion.5

Bibliography

Pubmed IDLast YearTitleAuthors
118304962002Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15).Fujino T et al
118414132002t(7;11)(p15;p15) Chronic myeloid leukaemia developed into blastic transformation showing a novel NUP98/HOXA11 fusion.Suzuki A et al
193380472009Juvenile myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98-HOXA11 fusion.Mizoguchi Y et al

Summary

Fusion gene

NUP98/HOXA11 NUP98 (11p15.4) HOXA11 (7p15.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(7;11)(p15;p15) NUP98/HOXA11

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3037/t(7;11)(p15;p15)-nup98-hoxa11