| Written | 2018-01 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3037 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute myeloblastic leukemia with maturation (FAB type M2)|Chronic myeloid leukemia, t(9;22)|Juvenile myelomonocytic leukemia |
| Genes involved and Proteins |
| Gene Name | NUP98 |
| Location | 11p15.4 |
| Gene Name | HOXA11 |
| Location | 7p15.2 |
| Bibliography |
| Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15) |
| Fujino T, Suzuki A, Ito Y, Ohyashiki K, Hatano Y, Miura I, Nakamura T |
| Blood 2002 Feb 15;99(4):1428-33 |
| PMID 11830496 |
| t(7;11)(p15;p15) Chronic myeloid leukaemia developed into blastic transformation showing a novel NUP98/HOXA11 fusion |
| Suzuki A, Ito Y, Sashida G, Honda S, Katagiri T, Fujino T, Nakamura T, Ohyashiki K |
| Br J Haematol 2002 Jan;116(1):170-2 |
| PMID 11841413 |
| Juvenile myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98-HOXA11 fusion |
| Mizoguchi Y, Fujita N, Taki T, Hayashi Y, Hamamoto K |
| Am J Hematol 2009 May;84(5):295-7 |
| PMID 19338047 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(7;11)(p15;p15) NUP98/HOXA11 | |
| External links |
| Mitelman database | t(7;11)(p15;p15) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sun Jul 12 19:48:00 CEST 2020 |
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