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t(7;14)(q21;q32) IGH/CDK6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3438
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic lymphocytic leukemia

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameCDK6
Location 7q21.2

Bibliography

In B-cell chronic lymphocytic leukemias, 7q21 translocations lead to overexpression of the CDK6 gene
Hayette S, Tigaud I, Callet-Bauchu E, Ffrench M, Gazzo S, Wahbi K, Callanan M, Felman P, Dumontet C, Magaud JP, Rimokh R
Blood 2003 Aug 15;102(4):1549-50
PMID 12900351
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;14)(q21;q32) IGH/CDK6

External links

IGH (14q32.33) CDK6 (7q21.2)

Mitelman databaset(7;14)(q21;q32) [Case List]    t(7;14)(q21;q32) [Transloc-MCList] IGH/CDK6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:06:50 CET 2018


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