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t(7;17)(p15;q22) MSI2/HOXA9

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3439
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic myeloid leukemia, t(9;22)

Genes involved and Proteins

Gene NameMSI2
Location 17q22
Gene NameHOXA9
Location 7p15.2

Bibliography

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23)
Barbouti A, Höglund M, Johansson B, Lassen C, Nilsson PG, Hagemeijer A, Mitelman F, Fioretos T
Cancer Res 2003 Mar 15;63(6):1202-6
PMID 12649177
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(7;17)(p15;q22) MSI2/HOXA9

External links

MSI2 (17q22) HOXA9 (7p15.2)

Mitelman databaset(7;17)(p15;q22) [Case List]    t(7;17)(p15;q22) [Transloc-MCList] MSI2/HOXA9 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Nov 6 14:06:52 CET 2018


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