t(7;22)(q34;q12) TRB/IL2RB

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
TRB
Location
7q34
Gene name
IL2RB
Location
22q12.3

Bibliography

Pubmed IDLast YearTitleAuthors
229480442012Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL.Le Noir S et al
286716882017The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia.Liu Y et al

Summary

Fusion gene

TRB/IL2RB TRB (7q34) IL2RB (22q12.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(7;22)(q34;q12) TRB/IL2RB

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3287/t(7;22)(q34;q12)-trb-il2rb