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t(8;9)(p11;q33) CNTRL/FGFR1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3440
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)|Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene NameCNTRL
Location 9q33.2
Gene NameFGFR1
Location 8p11.23

Bibliography

FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)
Guasch G, Mack GJ, Popovici C, Dastugue N, Birnbaum D, Rattner JB, Pébusque MJ
Blood 2000 Mar 1;95(5):1788-96
PMID 10688839
 
Identification of four new translocations involving FGFR1 in myeloid disorders
Sohal J, Chase A, Mould S, Corcoran M, Oscier D, Iqbal S, Parker S, Welborn J, Harris RI, Martinelli G, Montefusco V, Sinclair P, Wilkins BS, van den Berg H, Vanstraelen D, Goldman JM, Cross NC
Genes Chromosomes Cancer 2001 Oct;32(2):155-63
PMID 11550283
 
Common features of myeloproliferative disorders with t(8;9)(p12;q33) and CEP110-FGFR1 fusion: report of a new case and review of the literature
Mozziconacci MJ, Carbuccia N, Prebet T, Charbonnier A, Murati A, Vey N, Chaffanet M, Birnbaum D
Leuk Res 2008 Aug;32(8):1304-8
PMID 18096225
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;9)(p11;q33) CNTRL/FGFR1

External links

CNTRL (9q33.2) FGFR1 (8p11.23)

Mitelman databaset(8;9)(p11;q33) [Case List]    t(8;9)(p11;q33) [Transloc-MCList] CNTRL/FGFR1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:06:57 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.