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t(8;9)(q24;p13) MYC/ZBTB5

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2988

Clinics and Pathology

Disease Diffuse large B-cell lymphoma

Genes involved and Proteins

Gene NameMYC
Location 14q23.3
Gene NameZBTB5
Location 9p13.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas
Bertrand P, Bastard C, Maingonnat C, Jardin F, Maisonneuve C, Courel MN, Ruminy P, Picquenot JM, Tilly H
Leukemia 2007 Mar;21(3):515-23
PMID 17230227
 
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A, Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL, Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD, Marra MA
Blood 2013 Aug 15;122(7):1256-65
PMID 23699601
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;9)(q24;p13) MYC/ZBTB5

External links

MYC (14q23.3) ZBTB5 (9p13.2)

Mitelman databaset(8;9)(q24;p13) [Case List]    t(8;9)(q24;p13) [Transloc-MCList] MYC/ZBTB5 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:21:59 CET 2018


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jlhuret@AtlasGeneticsOncology.org.