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ins(12;8)(p13;q11q21)|t(8;12)(q12;p13) ETV6/LYN

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 3442
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloid leukemia, NOS|Idiopathic myelofibrosis

Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameLYN
Location 8q12.1


Identification of a novel TEL-Lyn fusion gene in primary myelofibrosis
Tanaka H, Takeuchi M, Takeda Y, Sakai S, Abe D, Ohwada C, Sakaida E, Shimizu N, Saito Y, Miyagi S, Iwama A, Nakaseko C
Leukemia 2010 Jan;24(1):197-200
PMID 19710703
Myeloproliferative neoplasm with eosinophilia and T-lymphoblastic lymphoma with ETV6-LYN gene fusion
Telford N, Alexander S, McGinn OJ, Williams M, Wood KM, Bloor A, Saha V
Blood Cancer J 2016 Apr 8;6:e412
PMID 27058227

Translocations implicated (Data extracted from papers in the Atlas)

 ins(12;8)(p13;q11q21)|t(8;12)(q12;p13) ETV6/LYN

External links

ETV6 (12p13.2) LYN (8q12.1)

Mitelman databaseins(12;8)(p13;q11q21)|t(8;12)(q12;p13) [Case List]    ins(12;8)(p13;q11q21)|t(8;12)(q12;p13) [Transloc-MCList] ETV6/LYN [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Tue Mar 12 13:14:17 CET 2019

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