Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(8;12)(q22;p13) ETV6/STK3

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Atlas_Id 2715
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameSTK3
Location 8q22.2


Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia
Ogawa S, Yokoyama Y, Suzukawa K, Nanmoku T, Kurita N, Seki M, Maie K, Suyama T, Takaiwa N, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S
Ann Hematol 2015 Aug;94(8):1431-3
PMID 25933678

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;12)(q22;p13) ETV6/STK3

External links

ETV6 (12p13.2) STK3 (8q22.2)

Mitelman databaset(8;12)(q22;p13)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Mon Sep 7 15:09:41 CEST 2020

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