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t(8;12)(q22;p13) ETV6/STK3

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2715
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameSTK3

Bibliography

Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia
Ogawa S, Yokoyama Y, Suzukawa K, Nanmoku T, Kurita N, Seki M, Maie K, Suyama T, Takaiwa N, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S
Ann Hematol 2015 Aug;94(8):1431-3
PMID 25933678
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;12)(q22;p13) ETV6/STK3

External links

ETV6 (12p13.2) STK3 ()

Mitelman databaset(8;12)(q22;p13) [Case List]    t(8;12)(q22;p13) [Transloc-MCList] ETV6/STK3 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon May 14 13:43:53 CEST 2018


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