Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3126 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Multiple myeloma |
Genes involved and Proteins |
Gene Name | PVT1 |
Location | 8q24.21 |
Gene Name | NBEA |
Location | 13q13.3 |
Bibliography |
Frequent PVT1 rearrangement and novel chimeric genes PVT1-NBEA and PVT1-WWOX occur in multiple myeloma with 8q24 abnormality |
Nagoshi H, Taki T, Hanamura I, Nitta M, Otsuki T, Nishida K, Okuda K, Sakamoto N, Kobayashi S, Yamamoto-Sugitani M, Tsutsumi Y, Kobayashi T, Matsumoto Y, Horiike S, Kuroda J, Taniwaki M |
Cancer Res 2012 Oct 1;72(19):4954-62 |
PMID 22869583 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(8;13)(q24;q13) PVT1/NBEA | |
External links |
Mitelman database | t(8;13)(q24;q13) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:28:12 CET 2020 |
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