| Written | 2018-01 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3126 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Multiple myeloma |
| Genes involved and Proteins |
| Gene Name | PVT1 |
| Location | 8q24.21 |
| Gene Name | NBEA |
| Location | 13q13.3 |
| Bibliography |
| Frequent PVT1 rearrangement and novel chimeric genes PVT1-NBEA and PVT1-WWOX occur in multiple myeloma with 8q24 abnormality |
| Nagoshi H, Taki T, Hanamura I, Nitta M, Otsuki T, Nishida K, Okuda K, Sakamoto N, Kobayashi S, Yamamoto-Sugitani M, Tsutsumi Y, Kobayashi T, Matsumoto Y, Horiike S, Kuroda J, Taniwaki M |
| Cancer Res 2012 Oct 1;72(19):4954-62 |
| PMID 22869583 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(8;13)(q24;q13) PVT1/NBEA | |
| External links |
| Mitelman database | t(8;13)(q24;q13) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sun Jul 12 19:48:09 CEST 2020 |
For comments and suggestions or contributions, please contact us