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t(8;17)(q24;q25) RNF213/MYC

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3151
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Anaplastic large cell lymphoma, systemic type

Genes involved and Proteins

Gene NameRNF213
Location 17q25.3
Gene NameMYC
Location 8q24.21

Bibliography

C-MYC rearrangement may induce an aggressive phenotype in anaplastic lymphoma kinase positive anaplastic large cell lymphoma: Identification of a novel fusion gene ALO17/C-MYC
Moritake H, Shimonodan H, Marutsuka K, Kamimura S, Kojima H, Nunoi H
Am J Hematol 2011 Jan;86(1):75-8
PMID 21080342
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;17)(q24;q25) RNF213/MYC

External links

RNF213 (17q25.3) MYC (8q24.21)

Mitelman databaset(8;17)(q24;q25) [Case List]    t(8;17)(q24;q25) [Transloc-MCList] RNF213/MYC [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:20:57 CEST 2018


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