Atlas of Genetics and Cytogenetics in Oncology and Haematology


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t(8;17)(q24;q25) RNF213/MYC


(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3151
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Anaplastic large cell lymphoma, systemic type

Genes involved and Proteins

Gene NameRNF213
Location 17q25.3
Gene NameMYC
Location 8q24.21

Bibliography

C-MYC rearrangement may induce an aggressive phenotype in anaplastic lymphoma kinase positive anaplastic large cell lymphoma: Identification of a novel fusion gene ALO17/C-MYC
Moritake H, Shimonodan H, Marutsuka K, Kamimura S, Kojima H, Nunoi H
Am J Hematol 2011 Jan;86(1):75-8
PMID 21080342
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;17)(q24;q25) RNF213/MYC


External links

RNF213 (17q25.3) MYC (8q24.21)

Mitelman databaset(8;17)(q24;q25)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Mon Sep 7 15:09:42 CEST 2020


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