t(8;19)(p11;q13) KAT6A/LEUTX

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute myelomonocytic leukemia (FAB type M4)

Genes Involved and Proteins

Gene name
KAT6A
Location
8p11.21
Gene name
LEUTX
Location
19q13.2

Highly cited references

Pubmed IDYearTitleCitations
327798582020Rapidly progressing acute myeloid leukemia with KAT6A-LEUTX fusion in a newborn.1
338133792021Therapy-related Myeloid Leukemia With the Translocation t(8;19)(p11;q13) Leading to a KAT6A-LEUTX Fusion Gene.0

Bibliography

Pubmed IDLast YearTitleAuthors
244460902014The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13).Chinen Y et al

Summary

Fusion gene

KAT6A/LEUTX KAT6A (8p11.21) LEUTX (19q13.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

t(8;19)(p11;q13) KAT6A/LEUTX

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2856/t(8;19)(p11;q13)-kat6a-leutx