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t(8;19)(q24;q13) BCL3/MYC

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2541
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease B-prolymphocytic leukemia

Genes involved and Proteins

Gene NameBCL3
Location 19q13.32
Gene NameMYC
Location 8q24.21

Bibliography

Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia
Gauwerky CE, Huebner K, Isobe M, Nowell PC, Croce CM
Proc Natl Acad Sci U S A 1989 Nov;86(22):8867-71
PMID 2682663
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;19)(q24;q13) BCL3/MYC

External links

BCL3 (19q13.32) MYC (8q24.21)

Mitelman databaset(8;19)(q24;q13) [Case List]    t(8;19)(q24;q13) [Transloc-MCList] BCL3/MYC [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:07:04 CET 2018


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