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t(9;11)(q33;q23) KMT2A/DAB2IP

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3449
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute monoblastic leukemia (FAB type M5)

Genes involved and Proteins

Gene NameKMT2A
Location 11q23.3
Gene NameDAB2IP
Location 9q33.2

Bibliography

Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a patient with de novo acute myeloid leukemia
von Bergh AR, Wijers PM, Groot AJ, van Zelderen-Bhola S, Falkenburg JH, Kluin PM, Schuuring E
Genes Chromosomes Cancer 2004 Apr;39(4):324-34
PMID 14978793
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(9;11)(q33;q23) KMT2A/DAB2IP

External links

KMT2A (11q23.3) DAB2IP (9q33.2)

Mitelman databaset(9;11)(q33;q23) [Case List]    t(9;11)(q33;q23) [Transloc-MCList] KMT2A/DAB2IP [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:14:55 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.