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t(9;14)(p13;q32) IGH/PAX5

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 2808
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Diffuse large B-cell lymphoma|Lymphoplasmacytic lymphoma|Mature B-cell neoplasm, NOS|Primary effusion lymphoma|Splenic marginal zone B-cell lymphoma|Waldenstrˆm macroglobulinemia

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NamePAX5
Location 9p13.2


Chromosomal rearrangement of the PAX-5 locus in lymphoplasmacytic lymphoma with t(9;14)(p13;q32)
Iida S, Rao PH, Ueda R, Chaganti RS, Dalla-Favera R
Leuk Lymphoma 1999 Jun;34(1-2):25-33
PMID 10350329
Lack of PAX5 rearrangements in lymphoplasmacytic lymphomas: reassessing the reported association with t(9;14)
Cook JR, Aguilera NI, Reshmi-Skarja S, Huang X, Yu Z, Gollin SM, Abbondanzo SL, Swerdlow SH
Hum Pathol 2004 Apr;35(4):447-54
PMID 15116325
The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene
Iida S, Rao PH, Nallasivam P, Hibshoosh H, Butler M, Louie DC, Dyomin V, Ohno H, Chaganti RS, Dalla-Favera R
Blood 1996 Dec 1;88(11):4110-7
PMID 8943844
PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements
Poppe B, De Paepe P, Michaux L, Dastugue N, Bastard C, Herens C, Moreau E, Cavazzini F, Yigit N, Van Limbergen H, De Paepe A, Praet M, De Wolf-Peeters C, Wlodarska I, Speleman F
Genes Chromosomes Cancer 2005 Oct;44(2):218-23
PMID 15942942
Translocation t(9;14)(p13;q32) in cases of splenic marginal zone lymphoma
Baró C, Salido M, Domingo A, Granada I, Colomo L, Serrano S, Solé F
Haematologica 2006 Sep;91(9):1289-91
PMID 16956840
A case of primary splenic large cell lymphoma with a t(9;14)(p13;q32)
Kawakami K, Amakawa R, Miyanishi S, Okumura A, Hayashi T, Kurata M, Ohno H, Ohno Y, Fukuhara S
Int J Hematol 1998 Feb;67(2):191-8
PMID 9631587
Expression of the PAX5/BSAP transcription factor in haematological tumour cells and further molecular characterization of the t(9;14)(p13;q32) translocation in B-cell non-Hodgkin's lymphoma
Hamada T, Yonetani N, Ueda C, Maesako Y, Akasaka H, Akasaka T, Ohno H, Kawakami K, Amakawa R, Okuma M
Br J Haematol 1998 Aug;102(3):691-700
PMID 9722295
Herpes virus type 8-negative primary effusion lymphoma associated with PAX-5 gene rearrangement and hepatitis C virus: a case report and review of the literature
Ichinohasama R, Miura I, Kobayashi N, Saitoh Y, DeCoteau JF, Saiki Y, Mori S, Kadin ME, Ooya K
Am J Surg Pathol 1998 Dec;22(12):1528-37
PMID 9850179

Translocations implicated (Data extracted from papers in the Atlas)

 t(9;14)(p13;q32) IGH/PAX5

External links

IGH (14q32.33) PAX5 (9p13.2)

Mitelman databaset(9;14)(p13;q32) [Case List]    t(9;14)(p13;q32) [Transloc-MCList] IGH/PAX5 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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