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t(9;14)(p21;q11) TRA/CDKN2A

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 3274

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameTRA
Location 10q26.13
Gene NameCDKN2A
Location 9p21.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute


The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia
Liu Y, Easton J, Shao Y, Maciaszek J, Wang Z, Wilkinson MR, McCastlain K, Edmonson M, Pounds SB, Shi L, Zhou X, Ma X, Sioson E, Li Y, Rusch M, Gupta P, Pei D, Cheng C, Smith MA, Auvil JG, Gerhard DS, Relling MV, Winick NJ, Carroll AJ, Heerema NA, Raetz E, Devidas M, Willman CL, Harvey RC, Carroll WL, Dunsmore KP, Winter SS, Wood BL, Sorrentino BP, Downing JR, Loh ML, Hunger SP, Zhang J, Mullighan CG
Nat Genet 2017 Aug;49(8):1211-1218
PMID 28671688
A new type of p16INK4/MTS1 gene transcript expressed in B-cell malignancies
Duro D, Bernard O, Della Valle V, Berger R, Larsen CJ
Oncogene 1995 Jul 6;11(1):21-9
PMID 7624129
Inactivation of the P16INK4/MTS1 gene by a chromosome translocation t(9;14)(p21-22;q11) in an acute lymphoblastic leukemia of B-cell type
Duro D, Bernard O, Della Valle V, Leblanc T, Berger R, Larsen CJ
Cancer Res 1996 Feb 15;56(4):848-54
PMID 8631023

Translocations implicated (Data extracted from papers in the Atlas)

 t(9;14)(p21;q11) TRA/CDKN2A

External links

TRA (10q26.13) CDKN2A (9p21.3)

Mitelman databaset(9;14)(p21;q11) [Case List]    t(9;14)(p21;q11) [Transloc-MCList] TRA/CDKN2A [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Wed Jan 10 17:22:12 CET 2018

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