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t(X;14)(p11;q32) IGH/GPR34

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 3460
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Diffuse large B-cell lymphoma|Extranodal marginal zone B-cell lymphoma|Nodal marginal zone B-cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameGPR34
Location Xp11.4


Baens M, Finalet Ferreiro J, Tousseyn T, Urbankova H, Michaux L, de Leval L, Dierickx D, Wolter P, Sagaert X, Vandenberghe P, De Wolf-Peeters C, Wlodarska I
4;q32 33) is recurrent in marginal zone lymphoma and up-regulates GPR34
PMID 22058210
t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth
Ansell SM, Akasaka T, McPhail E, Manske M, Braggio E, Price-Troska T, Ziesmer S, Secreto F, Fonseca R, Gupta M, Law M, Witzig TE, Dyer MJ, Dogan A, Cerhan JR, Novak AJ
Blood 2012 Nov 8;120(19):3949-57
PMID 22966169

Translocations implicated (Data extracted from papers in the Atlas)

 t(X;14)(p11;q32) IGH/GPR34

External links

IGH (14q32.33) GPR34 (Xp11.4)

Mitelman databaset(X;14)(p11;q32) [Case List]    t(X;14)(p11;q32) [Transloc-MCList] IGH/GPR34 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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