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t(10;11)(p12;q13) MLLT10/RNF169

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 2970

Clinics and Pathology

Disease Acute monoblastic leukemia (FAB type M5)

Genes involved and Proteins

Gene NameMLLT10
Location 10p12.31
Gene NameRNF169
Location 11q13.4

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute


Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23)
Ghosh S, Bartenhagen C, Okpanyi V, Gombert M, Binder V, Teigler-Schlegel A, Bradtke J, Röttgers S, Dugas M, Borkhardt A
Leukemia 2013 Aug;27(8):1745-8
PMID 23299548

Translocations implicated (Data extracted from papers in the Atlas)

 t(10;11)(p12;q13) MLLT10/RNF169

External links

MLLT10 (10p12.31) RNF169 (11q13.4)

Mitelman databaset(10;11)(p12;q13) [Case List]    t(10;11)(p12;q13) [Transloc-MCList] MLLT10/RNF169 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:24:38 CET 2018

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