| Written | 2018-01 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 2970 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute monoblastic leukemia (FAB type M5) |
| Genes involved and Proteins |
| Gene Name | MLLT10 |
| Location | 10p12.31 |
| Gene Name | RNF169 |
| Location | 11q13.4 |
| Bibliography |
| Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23) |
| Ghosh S, Bartenhagen C, Okpanyi V, Gombert M, Binder V, Teigler-Schlegel A, Bradtke J, Röttgers S, Dugas M, Borkhardt A |
| Leukemia 2013 Aug;27(8):1745-8 |
| PMID 23299548 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(10;11)(p12;q13) MLLT10/RNF169 | |
| External links |
| Mitelman database | t(10;11)(p12;q13) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sun Jul 12 19:48:25 CEST 2020 |
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