t(10;11)(p12;q13) MLLT10/RNF169

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2970
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute monoblastic leukemia (FAB type M5)

Genes involved and Proteins

Gene Name	MLLT10
Location	10p12.31

Gene Name	RNF169
Location	11q13.4

Bibliography

Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23)

Ghosh S, Bartenhagen C, Okpanyi V, Gombert M, Binder V, Teigler-Schlegel A, Bradtke J, Röttgers S, Dugas M, Borkhardt A

Leukemia 2013 Aug;27(8):1745-8

PMID 23299548

Translocations implicated (Data extracted from papers in the Atlas)

	t(10;11)(p12;q13) MLLT10/RNF169

External links

MLLT10 (10p12.31) RNF169 (11q13.4)

Mitelman database	t(10;11)(p12;q13) [Case List]    t(10;11)(p12;q13) [Transloc-MCList] MLLT10/RNF169 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 13 22:17:03 CET 2019

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