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t(10;11)(p12;q13) MLLT10/RNF169

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2970
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute monoblastic leukemia (FAB type M5)

Genes involved and Proteins

Gene NameMLLT10
Location 10p12.31
Gene NameRNF169
Location 11q13.4

Bibliography

Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23)
Ghosh S, Bartenhagen C, Okpanyi V, Gombert M, Binder V, Teigler-Schlegel A, Bradtke J, Röttgers S, Dugas M, Borkhardt A
Leukemia 2013 Aug;27(8):1745-8
PMID 23299548
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;11)(p12;q13) MLLT10/RNF169

External links

MLLT10 (10p12.31) RNF169 (11q13.4)

Mitelman databaset(10;11)(p12;q13) [Case List]    t(10;11)(p12;q13) [Transloc-MCList] MLLT10/RNF169 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:21:26 CEST 2018


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