Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(10;11)(q23;p15) NUP98/HHEX

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3036

Clinics and Pathology

Disease Acute myeloblastic leukemia with maturation (FAB type M2)

Genes involved and Proteins

Gene NameNUP98
Location 11p15.4
Gene NameHHEX
Location 10q23.33

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia
Jankovic D, Gorello P, Liu T, Ehret S, La Starza R, Desjobert C, Baty F, Brutsche M, Jayaraman PS, Santoro A, Mecucci C, Schwaller J
Blood 2008 Jun 15;111(12):5672-82
PMID 18388181
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;11)(q23;p15) NUP98/HHEX

External links

NUP98 (11p15.4) HHEX (10q23.33)

Mitelman databaset(10;11)(q23;p15) [Case List]    t(10;11)(q23;p15) [Transloc-MCList] NUP98/HHEX [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Feb 23 20:24:40 CET 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.