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t(10;11)(q23;p15) NUP98/HHEX

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3036
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with maturation (FAB type M2)

Genes involved and Proteins

Gene NameNUP98
Location 11p15.4
Gene NameHHEX
Location 10q23.33

Bibliography

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia
Jankovic D, Gorello P, Liu T, Ehret S, La Starza R, Desjobert C, Baty F, Brutsche M, Jayaraman PS, Santoro A, Mecucci C, Schwaller J
Blood 2008 Jun 15;111(12):5672-82
PMID 18388181
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(10;11)(q23;p15) NUP98/HHEX

External links

NUP98 (11p15.4) HHEX (10q23.33)

Mitelman databaset(10;11)(q23;p15) [Case List]    t(10;11)(q23;p15) [Transloc-MCList] NUP98/HHEX [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Nov 6 14:07:36 CET 2018


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