t(10;11)(q23;p15) NUP98/HHEX

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute myeloblastic leukemia with maturation (FAB type M2)

Genes Involved and Proteins

Gene name
NUP98
Location
11p15.4
Gene name
HHEX
Location
10q23.33

Highly cited references

Pubmed IDYearTitleCitations
343996522021Identification and genetic characterization of a NUP98-HHEX molecular rearrangement in a pediatric acute myeloid leukemia.0

Bibliography

Pubmed IDLast YearTitleAuthors
183881812008Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia.Jankovic D et al

Summary

Fusion gene

NUP98/HHEX NUP98 (11p15.4) HHEX (10q23.33)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(10;11)(q23;p15) NUP98/HHEX

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3036/t(10;11)(q23;p15)-nup98-hhex