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t(10;17)(p15;q21) MBTD1/ZMYND11

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2945
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes involved and Proteins

Gene NameMBTD1
Location 17q21.33
Gene NameZMYND11
Location 10p15.3

Bibliography

Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion
de Rooij JD, van den Heuvel-Eibrink MM, Kollen WJ, Sonneveld E, Kaspers GJ, Beverloo HB, Fornerod M, Pieters R, Zwaan CM
Genes Chromosomes Cancer 2016 Mar;55(3):237-41
PMID 26608508
 

Translocations implicated (Data extracted from papers in the Atlas)

 t(10;17)(p15;q21) MBTD1/ZMYND11

External links

MBTD1 (17q21.33) ZMYND11 (10p15.3)

Mitelman databaset(10;17)(p15;q21) [Case List]    t(10;17)(p15;q21) [Transloc-MCList] MBTD1/ZMYND11 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Mon Mar 25 16:51:56 CET 2019

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