Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 2945 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Acute myeloblastic leukemia with minimal differentiation (FAB type M0) |
Genes involved and Proteins |
Gene Name | MBTD1 |
Location | 17q21.33 |
Gene Name | ZMYND11 |
Location | 10p15.3 |
Bibliography |
Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion |
de Rooij JD, van den Heuvel-Eibrink MM, Kollen WJ, Sonneveld E, Kaspers GJ, Beverloo HB, Fornerod M, Pieters R, Zwaan CM |
Genes Chromosomes Cancer 2016 Mar;55(3):237-41 |
PMID 26608508 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(10;17)(p15;q21) MBTD1/ZMYND11 | |
External links |
Mitelman database | t(10;17)(p15;q21) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:28:32 CET 2020 |
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