t(10;17)(p15;q21) MBTD1/ZMYND11

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2945
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes involved and Proteins

Gene Name	MBTD1
Location	17q21.33

Gene Name	ZMYND11
Location	10p15.3

Bibliography

Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion

de Rooij JD, van den Heuvel-Eibrink MM, Kollen WJ, Sonneveld E, Kaspers GJ, Beverloo HB, Fornerod M, Pieters R, Zwaan CM

Genes Chromosomes Cancer 2016 Mar;55(3):237-41

PMID 26608508

Translocations implicated (Data extracted from papers in the Atlas)

	t(10;17)(p15;q21) MBTD1/ZMYND11

External links

MBTD1 (17q21.33) ZMYND11 (10p15.3)

Mitelman database	t(10;17)(p15;q21) [Case List]    t(10;17)(p15;q21) [Transloc-MCList] MBTD1/ZMYND11 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:22:59 CET 2018

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