Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(10;17)(p15;q21) MBTD1::ZMYND11

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Atlas_Id 2945
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes involved and Proteins

Gene NameMBTD1
Location 17q21.33
Gene NameZMYND11
Location 10p15.3


Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion
de Rooij JD, van den Heuvel-Eibrink MM, Kollen WJ, Sonneveld E, Kaspers GJ, Beverloo HB, Fornerod M, Pieters R, Zwaan CM
Genes Chromosomes Cancer 2016 Mar;55(3):237-41
PMID 26608508

Translocations implicated (Data extracted from papers in the Atlas)

 t(10;17)(p15;q21) MBTD1/ZMYND11

External links

MBTD1 (17q21.33) ZMYND11 (10p15.3)

Mitelman databaset(10;17)(p15;q21)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Oct 8 16:39:20 CEST 2021

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