| Written | 2018-01 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 2945 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute myeloblastic leukemia with minimal differentiation (FAB type M0) |
| Genes involved and Proteins |
| Gene Name | MBTD1 |
| Location | 17q21.33 |
| Gene Name | ZMYND11 |
| Location | 10p15.3 |
| Bibliography |
| Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion |
| de Rooij JD, van den Heuvel-Eibrink MM, Kollen WJ, Sonneveld E, Kaspers GJ, Beverloo HB, Fornerod M, Pieters R, Zwaan CM |
| Genes Chromosomes Cancer 2016 Mar;55(3):237-41 |
| PMID 26608508 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(10;17)(p15;q21) MBTD1/ZMYND11 | |
| External links |
| Mitelman database | t(10;17)(p15;q21) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sun Jul 12 19:48:28 CEST 2020 |
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