| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 1688 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Chronic myelomonocytic leukemia |
| Genes involved and Proteins |
| Gene Name | BCR |
| Location | 22q11.23 |
| Gene Name | RET |
| Location | 10q11.21 |
| Bibliography |
| RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation |
| Ballerini P, Struski S, Cresson C, Prade N, Toujani S, Deswarte C, Dobbelstein S, Petit A, Lapillonne H, Gautier EF, Demur C, Lippert E, Pages P, Mansat-De Mas V, Donadieu J, Huguet F, Dastugue N, Broccardo C, Perot C, Delabesse E |
| Leukemia 2012 Nov;26(11):2384-9 |
| PMID 22513837 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(10;22)(q11;q11) BCR/RET | |
| External links |
| Mitelman database | t(10;22)(q11;q11) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Sep 7 15:10:01 CEST 2020 |
For comments and suggestions or contributions, please contact us