t(10;22)(q11;q11) BCR/RET

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	1688
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Chronic myelomonocytic leukemia

Genes involved and Proteins

Gene Name	BCR
Location	22q11.23

Gene Name	RET
Location	10q11.21

Bibliography

RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation

Ballerini P, Struski S, Cresson C, Prade N, Toujani S, Deswarte C, Dobbelstein S, Petit A, Lapillonne H, Gautier EF, Demur C, Lippert E, Pages P, Mansat-De Mas V, Donadieu J, Huguet F, Dastugue N, Broccardo C, Perot C, Delabesse E

Leukemia 2012 Nov;26(11):2384-9

PMID 22513837

Translocations implicated (Data extracted from papers in the Atlas)

	t(10;22)(q11;q11) BCR/RET

External links

BCR (22q11.23) RET (10q11.21)

Mitelman database	t(10;22)(q11;q11) [Case List]    t(10;22)(q11;q11) [Transloc-MCList] BCR/RET [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jan 27 15:19:38 CET 2020

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