Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 1688 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Chronic myelomonocytic leukemia |
Genes involved and Proteins |
Gene Name | BCR |
Location | 22q11.23 |
Gene Name | RET |
Location | 10q11.21 |
Bibliography |
RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation |
Ballerini P, Struski S, Cresson C, Prade N, Toujani S, Deswarte C, Dobbelstein S, Petit A, Lapillonne H, Gautier EF, Demur C, Lippert E, Pages P, Mansat-De Mas V, Donadieu J, Huguet F, Dastugue N, Broccardo C, Perot C, Delabesse E |
Leukemia 2012 Nov;26(11):2384-9 |
PMID 22513837 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(10;22)(q11;q11) BCR/RET | |
External links |
Mitelman database | t(10;22)(q11;q11) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:28:34 CET 2020 |
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