KMT2A/USP2 (11q23)

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
KMT2A
Location
11q23.3
Gene name
USP2
Location
11q23.3

Highly cited references

Pubmed IDYearTitleCitations
308698172019Whole transcriptome sequencing reveals a KMT2A-USP2 fusion in infant acute myeloid leukemia.4
321968142020Cryptic and atypical KMT2A-USP2 and KMT2A-USP8 rearrangements identified by mate pair sequencing in infant and childhood leukemia.2
350877762021Aberrant GATA2 Activation in Pediatric B-Cell Acute Lymphoblastic Leukemia.1
357344122022Novel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias.0

Bibliography

Pubmed IDLast YearTitleAuthors
100879461999Trisomy 22 in acute myeloid leukemia: a marker for myeloid leukemia with monocytic features and cytogenetically cryptic inversion 16.Wong KF et al

Summary

Fusion gene

KMT2A/USP2 KMT2A (11q23.3) USP2 (11q23.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

KMT2A/USP2 (11q23)

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2904/kmt2a-usp2-(11q23)