Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(11;11)(q23;q23) RNF214/KMT2A

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 3153

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

Genes involved and Proteins

Gene NameRNF214
Location 11q23.3
Gene NameKMT2A
Location 11q23.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute


Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23)
Ghosh S, Bartenhagen C, Okpanyi V, Gombert M, Binder V, Teigler-Schlegel A, Bradtke J, Röttgers S, Dugas M, Borkhardt A
Leukemia 2013 Aug;27(8):1745-8
PMID 23299548

Translocations implicated (Data extracted from papers in the Atlas)

 t(11;11)(q23;q23) RNF214/KMT2A

External links

RNF214 (11q23.3) KMT2A (11q23.3)

Mitelman databaset(11;11)(q23;q23) [Case List]    t(11;11)(q23;q23) [Transloc-MCList] RNF214/KMT2A [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jan 10 17:22:33 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us